IodoMeyer-Schuster Rearrangement of 3-Alkoxy-2-yn-1-ols for β-Mono(Exclusively Z-Selective)-/di-Substituted α-Iodo-α,β-Unsaturated Esters
IR@CDRI: CSIR-Central Drug Research Institute, Lucknow
View Archive Info| Field | Value | |
| Creator |
Puri, Surendra
Thirupathi, Nuligonda Reddy, M S |
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| Date |
2015-05-08T06:18:22Z
2015-05-08T06:18:22Z 2014 |
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| Identifier |
Organic Letters, 2014, 16(20), 5246-9
http://hdl.handle.net/123456789/1446 |
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| Description |
We herein present the iodo Meyer-Schuster rearrangement of 3-alkoxypropargyl alcohols for α-Iodo-α,β-unsaturated esters using iodine or NIS in dichloromethane at ambient temperature. Substrates prepared from both aldehydes and ketones are found to be equally good feedstock for the reaction to produce β-mono- and -disubstituted products. Irrespective of the substitution, substrates prepared from aldehydes gave Z-isomers exclusively
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457297 bytes
application/pdf |
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| Language |
en
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| Relation |
CSIR-CDRI Communication No. 8800
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| Subject |
IodoMeyer-Schuster
β-Unsaturated Esters |
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| Title |
IodoMeyer-Schuster Rearrangement of 3-Alkoxy-2-yn-1-ols for β-Mono(Exclusively Z-Selective)-/di-Substituted α-Iodo-α,β-Unsaturated Esters
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Article
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