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Role of Synthetic Metabolic Modulators in Targeting Mitochondrial Hyperpolarization to Repress Cancer Associated Hallmark Traits

IR@IICB: CSIR-Indian Institute of Chemical Biology, Kolkata

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Title Role of Synthetic Metabolic Modulators in Targeting Mitochondrial Hyperpolarization to Repress Cancer Associated Hallmark Traits
 
Creator Saha, Suchandrima
 
Subject Drug Development/Diagnostics & Biotechnology
 
Description One of the major health problems earmarked in today‘s world is cancer and its frequency of occurrence and the rate at which it causes fatality, poses to be a global concern (1,2,3). A survey by World Health Organization (WHO) in the year 2008 suggested that grossly about 12.7 million people are affected with cancer and among them about 7.6 million people have already died from this deadly disease worldwide. Furthermore, WHO predicts that this situation will worsen by 2030 where an estimated 21.4 million new cases of cancer will arise, resulting in death of 13.2 million cancer afflicted patients annually (4). The present day options of surgery, chemotherapy and radiotherapy would hardly suffice to tackle this magnanimous problem and therefore, newer and rational strategies are of utmost importance (5, 6). Complementary and alternative medicines (CAMs) are already being considered for alleviating the problem of toxicity associated with conventional therapy and thus, helping to provide a better life and longevity to cancer patients.
 
Date 2016
 
Type Thesis
NonPeerReviewed
 
Format application/pdf
 
Identifier http://www.eprints.iicb.res.in/2731/1/THESIS.pdf
Saha, Suchandrima (2016) Role of Synthetic Metabolic Modulators in Targeting Mitochondrial Hyperpolarization to Repress Cancer Associated Hallmark Traits. PhD thesis, Jadavpur University.
 
Relation http://www.eprints.iicb.res.in/2731/