A two-dimensional coordination compound as a zinc ion selective luminescent probe for biological applications
Metadata of CSIR Papers
View Archive InfoField | Value | |
Title |
A two-dimensional coordination compound as a zinc ion selective luminescent probe for biological applications
|
|
Creator |
Dhara, K
Karan, S Ratha, J Roy, P Chandra, G Manassero, M Mallik, B Banerjee, P |
|
Subject |
Chemistry, Multidisciplinary
|
|
Description |
A 2D coordination compound {[Cu-2(HL)(N-3)]ClO4}(infinity) (1; H3L = 2,6-bis(hydroxyethyliminoethyl)4-methyl phenol) was synthesized and characterized by single-crystal X-ray diffraction to be a polymer in the crystalline state. Each (Cu-2(HL)(N-3)](+) species is connected to its adjacent unit by a bridging alkoxide oxygen atom of the ligand to form a helical propagation along the crystallographic a axis. The adjacent helical frameworks are connected by a ligand alcoholic oxygen atom along the crystallographic b axis to produce pleated 2D sheets. In solution, 1 dissociates into [Cu-2(HL)(2) (H3L]center dot 2H(2)O (2); the monomer displays high selectivity for Zn2+ and can be used in HEPES buffer (pH 7.4) as a zinc ion selective luminescent probe for biological application. The system shows a nearly 19-fold Zn2+ -selective chelation-enhanced fluorescence response in the working buffer. Application of 2 to cultured living cells (B16FI0 mouse melanoma and A375 human melanoma) and rat hippocampal slices was also studied by fluorescence microscopy.
|
|
Publisher |
WILEY-V C H VERLAG GMBHWEINHEIMPO BOX 10 11 61, D-69451 WEINHEIM, GERMANY
|
|
Date |
2011-09-20T12:12:32Z
2011-09-20T12:12:32Z 2007 |
|
Type |
Article
|
|
Identifier |
CHEMISTRY-AN ASIAN JOURNAL
1861-4728 http://hdl.handle.net/123456789/14314 |
|
Language |
English
|
|