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Bis- and trisuracil nucleosides with nucleobases anchored to 11-, 12-, and 16-membered macrocyclic scaffolds: Synthesis and aggregation study

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Title Bis- and trisuracil nucleosides with nucleobases anchored to 11-, 12-, and 16-membered macrocyclic scaffolds: Synthesis and aggregation study
 
Creator Sengupta, J
Mukhopadhyay, R
Bhattacharjya, A
 
Subject Chemistry, Organic
 
Description Bis- and trisuracil nucleosides, in which the nucleobases are anchored to isoxazoline ring-fused 11-, 12-, and 16-membered macrooxacycles, were synthesized by nucleosidation of 1,2-isopropylidenefuranose ring-fused macrocycles. The nucleosides exhibited spherical and fiber-like morphologies in water. In one case, the morphology was significantly altered by complexation with an adenine nucleoside via complementary base pairing.
 
Publisher AMER CHEMICAL SOCWASHINGTON1155 16TH ST, NW, WASHINGTON, DC 20036 USA
 
Date 2011-09-20T12:12:35Z
2011-09-20T12:12:35Z
2007
 
Type Article
 
Identifier JOURNAL OF ORGANIC CHEMISTRY
0022-3263
http://hdl.handle.net/123456789/14330
 
Language English