Ascorbate Peroxidase from Leishmania major Controls the Virulence of Infective Stage of Promastigotes by Regulating Oxidative Stress
IR@IICB: CSIR-Indian Institute of Chemical Biology, Kolkata
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Title |
Ascorbate Peroxidase from Leishmania major Controls
the Virulence of Infective Stage of Promastigotes by
Regulating Oxidative Stress
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Creator |
Pal, Swati
Dolai, Subhankar Yadav, Rajesh K Adak, Subrata |
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Subject |
Structural Biology & Bioinformatics
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Description |
Peroxidase represents a heterogeneous group of distinct enzyme family that plays extremely diverse
biological functions. Ascorbate peroxidase from Leishmania major (LmAPX) has been shown to be central to the redox
defense system of Leishmania. To investigate further its exact physiological role in Leishmania, we attempted to create
LmAPX -knockout mutants by gene replacement in L. major strains.
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Date |
2010
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Type |
Article
PeerReviewed |
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Format |
application/pdf
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Identifier |
http://www.eprints.iicb.res.in/18/1/PLOS_ONE_5(6)_Article_Number_e11271;2010[65].pdf
Pal, Swati and Dolai, Subhankar and Yadav, Rajesh K and Adak, Subrata (2010) Ascorbate Peroxidase from Leishmania major Controls the Virulence of Infective Stage of Promastigotes by Regulating Oxidative Stress. PLoS One, 5 (6). e11271. |
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Relation |
http://dx.doi.org/10.1371/journal.pone.0011271
http://www.eprints.iicb.res.in/18/ |
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