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14-Deoxyandrographolide Desensitizes Hepatocytes to Tumour Necrosis Factoralpha-induced Apoptosis through Calcium-Dependent Tumour Necrosis Factor Receptor Superfamily member 1A release via the NO/cGMP pathway

IR@IICB: CSIR-Indian Institute of Chemical Biology, Kolkata

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Title 14-Deoxyandrographolide Desensitizes Hepatocytes to Tumour Necrosis Factoralpha-induced Apoptosis through Calcium-Dependent Tumour Necrosis Factor Receptor Superfamily member 1A release via the NO/cGMP pathway
 
Creator Roy, DN
Mandal, S
Mukhopadhyay, S
Biswas, Tuli
 
Subject Chemistry
 
Description 14-DAG, 14-deoxyandrographolide; ActD, actinomycin D; AG, andrographolide; D-GalN, D-galactosamine; DISC, death-inducing signalling complex; DMSO, dimethyl sulphoxide; DTT, dithiothreitol; ER, endoplasmic reticulum; FADD, fas-associated death domain; FBS, fetal bovine serum; FITC, fluorescein isothiocyanate; L-NAME, L-nitro-arginine methyl ester; MTT, 3-(4,5-dimethylthiazol-2-yl)-2,5-diphenyltetrazolium bromide; NF-kb, nuclear factor kappa beta; NO, nitric oxide; OH, hydroxyl; PAF, platelet-activating factor; PMSF, phenylmethylsulphonyl fluoride; RPMI-1640, Roswell Park Memorial Institute-1640; SDS, sodium dodecyl sulphate; TNFRSF1A (TNFR1), tumour necrosis factor receptor 1; TNFRSF1B (TNFR2), tumour necrosis factor receptor 2; TNF-a, tumour necrosis factor-alpha; TRADD, tumour necrosis factor receptor-associated death domain
 
Publisher Blackwell Publishing
 
Date 2010
 
Type Article
PeerReviewed
 
Format application/pdf
 
Identifier http://www.eprints.iicb.res.in/62/1/BRITISH_JOURNAL_OF_PHARMACOLOGY_160_(7)1823%2D1843_;2010[51].pdf
Roy, DN and Mandal, S and Mukhopadhyay, S and Biswas, Tuli (2010) 14-Deoxyandrographolide Desensitizes Hepatocytes to Tumour Necrosis Factoralpha-induced Apoptosis through Calcium-Dependent Tumour Necrosis Factor Receptor Superfamily member 1A release via the NO/cGMP pathway. British Journal Of Pharmacology, 160 (7). pp. 1823-1843.
 
Relation http:/dx.doi.org/10.1111/j.1476-5381.2010.00836.x
http://www.eprints.iicb.res.in/62/