The Use of Neem for Controlling Gastric Hyperacidity and Ulcer
IR@IICB: CSIR-Indian Institute of Chemical Biology, Kolkata
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Title |
The Use of Neem for Controlling Gastric
Hyperacidity and Ulcer
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Creator |
Maity, Pallab
Biswas, Kaushik Chattopadhyay, Ishita Banerjee, Ranajit K Bandyopadhyay, Uday |
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Subject |
Cell Biology & Physiology
Infectious Diseases and Immunology |
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Description |
H2-receptor blockers and proton pump inhibitors are now used extensively to control gastric and duodenal ulcer,
inflammation and pain, but these drugs have limitations and are not always affordable. The development of
novel nontoxic antiulcer drugs, including from medicinal plants, is therefore desirable, and Azadirachta indica
A. Juss, commonly known as Neem, is known to have potent gastroprotective and antiulcer effects. This review
deals with the pharmacological and biochemical studies carried out regarding the antiulcer activities of Neem
extracts and their mechanism of action, including the inhibition of acid secretion. A comparison with ranitidine
and omeprazole in some animal models has been included and clinical studies, where available, have also been
incorporated, along with a safety evaluation. Neem bark extract has the potential for the development of novel
medicines for the therapeutic control of gastric hyperacidity and ulcer. Copyright © 2009 John Wiley & Sons, Ltd.
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Publisher |
John Wiley & Sons
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Date |
2009
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Type |
Article
PeerReviewed |
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Format |
application/pdf
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Identifier |
http://www.eprints.iicb.res.in/254/1/PHYTOTHERAPY_RESEARCH%2C_23(6)%2C_747%2D755%2C2009[65].pdf
Maity, Pallab and Biswas, Kaushik and Chattopadhyay, Ishita and Banerjee, Ranajit K and Bandyopadhyay, Uday (2009) The Use of Neem for Controlling Gastric Hyperacidity and Ulcer. Phytotherapy Research, 23 (6). pp. 747-755. ISSN 0951-418X |
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Relation |
http://dx.doi.org/10.1002/ptr.2721
http://www.eprints.iicb.res.in/254/ |
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