Bis- and Trisuracil Nucleosides with Nucleobases Anchored to 11-, 12-, and 16-Membered Macrocyclic Scaffolds: Synthesis and Aggregation Study
IR@IICB: CSIR-Indian Institute of Chemical Biology, Kolkata
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| Title |
Bis- and Trisuracil Nucleosides with Nucleobases Anchored to 11-, 12-, and 16-Membered Macrocyclic Scaffolds: Synthesis and
Aggregation Study
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| Creator |
Sengupta, Jhimli
Mukhopadhyay, Ranjan Bhattacharjya, Anup |
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| Subject |
Chemistry
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| Description |
Interaction of nucleobases with themselves and other molecules has a profound role in biological systems. Supramolecular assemblies made out of derivatives of nucleobases have been examined by various techniques, and different motifs arising out of hydrogen bonding, stacking, and hydrophobic interactions have been proposed.1 It is well-established that molecular systems such as lipids or other amphiphilic molecules containing both polar and apolar units such as oligomethylene chains lead
to ordered structures in water primarily due to the involvement of both hydrogen bonding and hydrophobic interactions. Supramolecular complexes arising out of complementary base pairing between non-nucleoside molecules such as melamine and cyanuric acid derivatives have been extensively studied.
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| Date |
2007
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| Type |
Article
PeerReviewed |
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| Format |
application/pdf
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| Identifier |
http://www.eprints.iicb.res.in/345/1/JOURNAL_OF_ORGANIC_CHEMISTRY%2C_72(13)%2C__4621%2D4625[75].pdf
Sengupta, Jhimli and Mukhopadhyay, Ranjan and Bhattacharjya, Anup (2007) Bis- and Trisuracil Nucleosides with Nucleobases Anchored to 11-, 12-, and 16-Membered Macrocyclic Scaffolds: Synthesis and Aggregation Study. Journal of Organic Chemistry, 72 (13). pp. 4621-4625. |
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| Relation |
http://dx.doi.org/10.1021/jo062554b
http://www.eprints.iicb.res.in/345/ |
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