Divergent Cycloaddition and Ring-Closing Metathesis Approaches to Indolizidine and Pyrrolo[1,2-a]azepine Skeletons from a Chiral Precursor: An Expeditious Route to (-)-8-epi-Swainsonine Triacetate
IR@IICB: CSIR-Indian Institute of Chemical Biology, Kolkata
View Archive Info| Field | Value | |
| Title |
Divergent Cycloaddition and Ring-Closing Metathesis Approaches to Indolizidine and Pyrrolo[1,2-a]azepine
Skeletons from a Chiral Precursor: An Expeditious Route to
(-)-8-epi-Swainsonine Triacetate
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| Creator |
Nath, Madhumita
Mukhopadhyay, Ranjan Bhattacharjya, Anup |
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| Subject |
Chemistry
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| Description |
A divergent strategy for the synthesis of diverse azabicyclic ring systems has been developed in which a chiral N-allylpyrrolidine derivative,
obtained from a carbohydrate precursor was converted to (-)-8-epi-swainsonine triacetate by RCM and to a pyrrolo[1,2-a]azepine derivative and a 3-hydroxymethyl-substituted indolizidine by N-allylcarbohydrate nitrone and nitrile oxide cycloadditions.
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| Date |
2006
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| Type |
Article
PeerReviewed |
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| Format |
application/pdf
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| Identifier |
http://www.eprints.iicb.res.in/451/1/ORGANIC_LETTERS%2C_8(_2)%2C__317%2D320_[141].pdf
Nath, Madhumita and Mukhopadhyay, Ranjan and Bhattacharjya, Anup (2006) Divergent Cycloaddition and Ring-Closing Metathesis Approaches to Indolizidine and Pyrrolo[1,2-a]azepine Skeletons from a Chiral Precursor: An Expeditious Route to (-)-8-epi-Swainsonine Triacetate. Organic Letters, 8 (2). pp. 317-320. |
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| Relation |
http://dx.doi.org/10.1021/ol052716a CCC: $33.50
http://www.eprints.iicb.res.in/451/ |
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