Studies Towards The Synthesis of Enantiomerically Pure Heterocycles From Carbohydrate Derivatives
IR@IICB: CSIR-Indian Institute of Chemical Biology, Kolkata
View Archive Info| Field | Value | |
| Title |
Studies Towards The Synthesis of Enantiomerically Pure Heterocycles From Carbohydrate Derivatives
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| Creator |
Nath, Madhumita
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| Subject |
Chemistry
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| Description |
Carbohydrate derivatives provide a convenient source for the synthesis of enantiopure chiral compounds. Literature is replete with examples of natural products or other useful compounds synthesized by using the carbohydrate chiral pool. This dissertation primarily deals with the synthesis of some azabicyclic skeletons and an approach to zoapatanol, all incorporating either chiral cyclic amine or cyclic ether moieties, from carbohydrate derived precursors. The methodologies for these synthetic exercises involved the application of three major well known cyclization reactions − intramolecular nitrone cycloaddition, intramolecular nitrile oxide cycloaddition and ring closing metathesis. Short discussions on the specific aspects of these reactions relevant to the work described in the dissertation are presented in this chapter. In keeping with the main objective of the work, major emphasis has been given to reported strategies based on carbohydrate derivatives.
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| Date |
2007
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| Type |
Thesis
NonPeerReviewed |
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| Format |
application/pdf
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| Identifier |
http://www.eprints.iicb.res.in/581/1/Madhumita_thesis%2DCD.pdf
Nath, Madhumita (2007) Studies Towards The Synthesis of Enantiomerically Pure Heterocycles From Carbohydrate Derivatives. PhD thesis, Jadavpur University. |
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| Relation |
http://www.eprints.iicb.res.in/581/
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