Trigonella foenum graecum (Fenugreek) Seed Extract as an Antineoplastic Agent
IR@IICB: CSIR-Indian Institute of Chemical Biology, KolkataView Archive Info
Trigonella foenum graecum (Fenugreek) Seed
Extract as an Antineoplastic Agent
Vedasiromoni, J R
Sahu, Niranjan P
Sharma, R M
Ganguly, D K
The antineoplastic effect of Trigonella foenum graecum seed extract has been evaluated in the Ehrlich
ascites carcinoma (EAC) model in Balb-C mice. Intra-peritoneal administration of the alcohol extract of
the seed both before and after inoculation of EAC cell in mice produced more than 70% inhibition of
tumour cell growth with respect to the control. Treatment with the extract was found to enhance both
the peritoneal exudate cell and macrophage cell counts. The extract also produced a significant antiin-
flammatory effect. We report here the antiinflammatory and antineoplastic effects, of Trigonella foenum
graecum seed extract.
Sur, Pratima and Das, Minati and Gomes, Aparna and Vedasiromoni, J R and Sahu, Niranjan P and Banerjee, S and Sharma, R M and Ganguly, D K (2001) Trigonella foenum graecum (Fenugreek) Seed Extract as an Antineoplastic Agent. PHYTOTHERAPY RESEARCH, 15 (3). pp. 257-259.