Biotransformation of lantadene A (22�-angeloyloxy-3-oxoolean-12-en-28-oic acid), the pentacyclic triterpenoid, by Alcaligenes faecalis
IR@IICB: CSIR-Indian Institute of Chemical Biology, Kolkata
View Archive Info| Field | Value | |
| Title |
Biotransformation of lantadene A
(22�-angeloyloxy-3-oxoolean-12-en-28-oic acid), the pentacyclic
triterpenoid, by Alcaligenes faecalis
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| Creator |
Singh, Anita
Sharma, Om P Dawra, Rajinder K Kanwar, Sarbjit S Mahato, Shashi B |
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| Subject |
Chemistry
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| Description |
A bacterial strain capable of biotransformation of lantadene A (22�-angeloyloxy-3-oxo-olean-12-en-28-oic acid),
the pentacyclic hepatotoxin of lantana (Lantana camara var. aculeata) has been isolated from soil using lantadene
A as the sole carbon source. The organism is Gram negative, rod shaped, motile, catalase positive and has been
identified as Alcaligenes faecalis. The isolate has been found to be specific for lantadene A and did not utilize
lantadene B. In studies using sucrose as an additional carbon source, A. faecalis elicited biotransformation of
lantadene A to its trans isomer 22�-tigloyloxy-3-oxoolean-12-en-28-oic acid, designated as lantadene X and two
other minor metabolites which could not be isolated in pure state.
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| Publisher |
Kluwer
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| Date |
1999
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| Type |
Article
PeerReviewed |
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| Format |
application/pdf
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| Identifier |
http://www.eprints.iicb.res.in/660/1/BIODEGRADATION_10_(5)_373%2D381;1999[91].pdf
Singh, Anita and Sharma, Om P and Dawra, Rajinder K and Kanwar, Sarbjit S and Mahato, Shashi B (1999) Biotransformation of lantadene A (22�-angeloyloxy-3-oxoolean-12-en-28-oic acid), the pentacyclic triterpenoid, by Alcaligenes faecalis. Biodegradation, 10 (5). pp. 373-381. |
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| Relation |
http://dx.doi.org/
http://www.eprints.iicb.res.in/660/ |
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