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Synthesis of a Versatile Tetrasaccharlde of Slalyl Lex and Lex Antigens.

IR@IICB: CSIR-Indian Institute of Chemical Biology, Kolkata

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Title Synthesis of a Versatile Tetrasaccharlde of Slalyl Lex and Lex Antigens.
 
Creator Chowdhury, Uday Shankar
 
Subject Chemistry
 
Description Benzyl q-o- [ 2, q, 6-tri-O-benzyl-3-O- ( q-methoxybenzyl } -/3- D-galactopyranosyl]-2-~3,6-tri-O-b~zyl-/J-D-g~copyranoside (q) was synthesised from benzyl lact~'~ide (2) via regioselective protection of 3'-OH with q-methoxybenzyl group. Oxidative deprotection of q afforded the valuable acceptor 5. The trisaccharide 7 was obtained through coupling of 5 and phenyl 2-deoxy-3,q,6-tri-O-acetyl-2-pht-halimido-l-thio-#-D-glucopyranoside (6]. The desired tetrasaccha- ride I was built up through fucosylation of the benzylidene deri- vative 11 o b t a i n e d from 7.
 
Date 1996
 
Type Article
PeerReviewed
 
Format application/pdf
 
Identifier http://www.eprints.iicb.res.in/726/1/TETRAHEDRON%2C__52_(_39)%2C_12775%2D12782[16].pdf
Chowdhury, Uday Shankar (1996) Synthesis of a Versatile Tetrasaccharlde of Slalyl Lex and Lex Antigens. Tetrahedron, 52 (39). pp. 12775-12782.
 
Relation http://dx.doi.org/10.1016/0040-4020(96)00759-4
http://www.eprints.iicb.res.in/726/