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Inhibition of Tumour Growth and Inflammation by Consumption of Tea

IR@IICB: CSIR-Indian Institute of Chemical Biology, Kolkata

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Title Inhibition of Tumour Growth and Inflammation by Consumption of Tea
 
Creator Das, Minati
Sur, Pratima
Gomes, Aparna
Vedasiromoni, J R
Ganguly, Dilip K
 
Subject Drug Development/Diagnostics & Biotechnology
 
Description The antitumour effect of tea was evaluated in the 3-methylcholanthrene (3-MC) induced solid tumour model in mice. Both black and green tea inhibited tumour growth and prevented metastasis. Histopathological study showed that tea treatment was able to reduce malignancy. Superoxide dismutase (SOD), a free radical scavenger, was found to be significantly increased in the serum of mice administered tea. Moreover, tea extracts were able to reduce the level of thiobarbituric acid reactive substance (TBARS) in the sera of mice. Tea extracts (both black and green) also showed antiinflammatory activity in the carrageenan- induced paw oedema model in the rat.
 
Publisher John Wiley & Sons
 
Date 2002
 
Type Article
PeerReviewed
 
Format application/pdf
 
Identifier http://www.eprints.iicb.res.in/792/1/PHYTOTHERAPY_RESEARCH__16_(_Supplement_1)S40%2DS44;2002[65].pdf
Das, Minati and Sur, Pratima and Gomes, Aparna and Vedasiromoni, J R and Ganguly, Dilip K (2002) Inhibition of Tumour Growth and Inflammation by Consumption of Tea. Phytotherapy Research, 16 (Supp.1). pp. 540-544. ISSN 0951-418X
 
Relation http://dx.doi.org/10.1002/ptr.797
http://www.eprints.iicb.res.in/792/