A facile approach towards enantiomerically pure masked β-amino alcohols
IR@IIIM: CSIR-Indian Institute of Integrative Medicine, Jammu
View Archive Info| Field | Value | |
| Title |
A facile approach towards enantiomerically pure masked β-amino alcohols
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| Creator |
Gupta, Pankaj
Shah, Bhahwal Ali Parshad, Rajinder Qazi, Ghulam Nabi Taneja, Subhash Chandra |
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| Subject |
Chemical Sciences
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| Description |
b-Amino alcohols are bioactive molecules, used also as catalysts in asymmetric C–C bond formation. While asymmetric synthesis has been the preferred route for their preparation, there was always been a need to develop a facile methodology involving environmentally friendly transformations. Masked amines in the form of phthalimide alcohols, prepared via a fast coupling reaction in an ionic liquid as a reusable reaction media together with reduction and an efficient biocatalytic resolution, offer a green methodology for enantiomerically pure products(ee . 99%, 50 g L21).
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| Date |
2007
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| Type |
Article
PeerReviewed |
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| Format |
application/pdf
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| Identifier |
http://iiim.csircentral.net/186/1/10.1039b701192j.pdf
Gupta, Pankaj and Shah, Bhahwal Ali and Parshad, Rajinder and Qazi, Ghulam Nabi and Taneja, Subhash Chandra (2007) A facile approach towards enantiomerically pure masked β-amino alcohols. Green Chemistry, 9 (10). p. 1120. ISSN 1463-9262 |
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| Relation |
http://dx.doi.org/10.1039/b701192j
http://iiim.csircentral.net/186/ |
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