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4beta-Chloroethylaminopyrimidines and the formation of imidazolidino [1,2-c] pyrimidines on acid treatment of 4-bis-beta-hydroxyethylaminopyrimidines

IR@CDRI: CSIR-Central Drug Research Institute, Lucknow

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Field Value
 
Creator Nagpal, K L
Dhar, M M
 
Date 2010-08-23T10:25:32Z
2010-08-23T10:25:32Z
1967
 
Identifier Tetrahedron, 1967,23,1297
http://hdl.handle.net/123456789/558
 
Description During synthesis aimed at obtaining 4-beta-chloroethylamino and 4-bis-beta-chloroethylamino pyrimidines, it has been found that treatment of 2-chloro-4-bis-beta-hydroxyethylaminopyrimidine with hydrochloric acid or of 4-bis-beta-hydroxyethylamino-2-mercaptopyrimidine with chloroacetic acid and hydrochloric acid yields 1-beta-hydroxyethyl-5-oxo-imidazolidino [1.2-c] pyrimidine.
 
Format 1587429 bytes
application/pdf
 
Language en
 
Subject 4-beta-chloroethylamino
4-bis-beta-chloroethylamino
pyrimidines
2-chloro-4-bis-beta-hydroxyethylaminopyrimidine
 
Title 4beta-Chloroethylaminopyrimidines and the formation of imidazolidino [1,2-c] pyrimidines on acid treatment of 4-bis-beta-hydroxyethylaminopyrimidines
 
Type Article