4beta-Chloroethylaminopyrimidines and the formation of imidazolidino [1,2-c] pyrimidines on acid treatment of 4-bis-beta-hydroxyethylaminopyrimidines
IR@CDRI: CSIR-Central Drug Research Institute, Lucknow
View Archive InfoField | Value | |
Creator |
Nagpal, K L
Dhar, M M |
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Date |
2010-08-23T10:25:32Z
2010-08-23T10:25:32Z 1967 |
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Identifier |
Tetrahedron, 1967,23,1297
http://hdl.handle.net/123456789/558 |
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Description |
During synthesis aimed at obtaining 4-beta-chloroethylamino and 4-bis-beta-chloroethylamino pyrimidines, it has been found that treatment of 2-chloro-4-bis-beta-hydroxyethylaminopyrimidine with hydrochloric acid or of 4-bis-beta-hydroxyethylamino-2-mercaptopyrimidine with chloroacetic acid and hydrochloric acid yields 1-beta-hydroxyethyl-5-oxo-imidazolidino [1.2-c] pyrimidine.
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Format |
1587429 bytes
application/pdf |
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Language |
en
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Subject |
4-beta-chloroethylamino
4-bis-beta-chloroethylamino pyrimidines 2-chloro-4-bis-beta-hydroxyethylaminopyrimidine |
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Title |
4beta-Chloroethylaminopyrimidines and the formation of imidazolidino [1,2-c] pyrimidines on acid treatment of 4-bis-beta-hydroxyethylaminopyrimidines
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Type |
Article
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