dbSMR: a novel resource of genome-wide SNPs affecting microRNA mediated regulation
IR@IGIB: CSIR-Institute of Genomics & Integrative Biology, New DelhiView Archive Info
dbSMR: a novel resource of genome-wide SNPs affecting
microRNA mediated regulation
Brahmachari, Samir K.
G1 Genome informatics (General)
Background: MicroRNAs (miRNAs) regulate several biological processes through post-
transcriptional gene silencing. The efficiency of binding of miRNAs to target transcripts depends on
the sequence as well as intramolecular structure of the transcript. Single Nucleotide
Polymorphisms (SNPs) can contribute to alterations in the structure of regions flanking them,
thereby influencing the accessibility for miRNA binding.
Hariharan, Manoj and Scaria, Vinod and Brahmachari, Samir K. (2009) dbSMR: a novel resource of genome-wide SNPs affecting microRNA mediated regulation. BMC Bioinformatics, 10. ISSN 1471-2105