miRvar: A Comprehensive Database for Genomic Variations in microRNAs
IR@IGIB: CSIR-Institute of Genomics & Integrative Biology, New Delhi
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Title |
miRvar: A Comprehensive Database for Genomic
Variations in microRNAs
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Creator |
Bhartiya, Deeksha
Laddha, Saurabh V. Mukhopadhyay, Arijit Scaria, Vinod |
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Subject |
G1 Genome informatics (General)
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Description |
ABSTRACT: microRNAs are a recently discovered and well studied class of small noncoding
functional RNAs. The regulatory role of microRNAs (miRNAs) has been well studied in a wide
variety of biological processes but there have been no systematic effort to understand and analyze
the genetic variations in miRNA loci and study its functional consequences. We have
comprehensively curated genetic variations in miRNA loci in the human genome and established a
computational pipeline to assess potential functional consequences of these variants along with
methods for systematic curation and reporting of variations in these loci. The data is made
available on the Leiden Open (source) Variation Database (LOVD) platform at
http://genome.igib.res.in/mirlovd to provide ease of aggregation and analysis and is open for
community curation efforts. ©2011 Wiley-Liss, Inc.
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Date |
2011-02-24
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Type |
Article
PeerReviewed |
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Format |
application/pdf
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Identifier |
http://openaccess.igib.res.in/97/1/21482_ftp.pdf
Bhartiya, Deeksha and Laddha, Saurabh V. and Mukhopadhyay, Arijit and Scaria, Vinod (2011) miRvar: A Comprehensive Database for Genomic Variations in microRNAs. PubMed, 32 (6). E2226-E2245. |
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Relation |
http://openaccess.igib.res.in/97/
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