Racemic Resolution of some dl-Amino Acids using Aspergillus fumigatusl-Amino Acid Oxidase
IR@NEIST: CSIR-North East Institute of Science and Technology, Jorhat
View Archive Info| Field | Value | |
| Title |
Racemic Resolution of some dl-Amino Acids using Aspergillus fumigatusl-Amino Acid Oxidase
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| Creator |
SINGH , S
GOGOI , B K BEZBARUAH , R L |
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| Subject |
Biotechnology
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| Description |
The ability of Aspergillus fumigatus L-amino
acid oxidase (L-aao) to cause the resolution of racemic
mixtures of DL-amino acids was investigated with DL-alanine,
DL-phenylalanine, DL-tyrosine, and DL-aspartic acid.A
chiralcolumn,Crownpak CR?wasusedfortheanalysisof
the amino acids. The enzyme was able to cause the resolution
of the three DL-amino acids resulting in the production
of optically pure D-alanine (100% resolution),
D-phenylalanine (80.2%), and D-tyrosine (84.1%), respectively.
The optically pure D-amino acids have many uses
and thus can be exploited industrially. This is the first
report of the use of A. fumigatus L-amino acid oxidase for
racemic resolution of DL-amino acids.
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| Date |
2011
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| Type |
Article
PeerReviewed |
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| Format |
application/pdf
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| Identifier |
http://neist.csircentral.net/119/1/2937.pdf
SINGH , S and GOGOI , B K and BEZBARUAH , R L (2011) Racemic Resolution of some dl-Amino Acids using Aspergillus fumigatusl-Amino Acid Oxidase. Current Microbiology, 63. pp. 94-99. |
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| Relation |
http://neist.csircentral.net/119/
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