A simple, green and one-pot four-component synthesis of 1,4-dihydropyridines and their aromatization
IR@NEIST: CSIR-North East Institute of Science and Technology, Jorhat
View Archive Info| Field | Value | |
| Title |
A simple, green and one-pot four-component synthesis of 1,4-dihydropyridines and their aromatization
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| Creator |
Das , Sharma S
Hazarika, P Konwar, D |
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| Subject |
Organic Chemistry
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| Description |
A simple, green and cost-effective protocol was achieved for the solvent free synthesis of 1,4-dihydropyridines catalyzed by
AlCl3 Æ 6H2O as a mild and effective catalyst at 60 �C in high yields. 1,4-Dihydropyridines thus formed were aromatized to pyridines
by in situ generation of HOCl employing AlCl3 Æ 6H2O/H2O2/H2O/EtOH as an excellent reagent system under domestic microwave irradiation
(MWI). Both the synthesis and oxidation steps were efficiently accomplished in one-pot four-component fashion following the
same protocol
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| Date |
2008
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| Type |
Article
PeerReviewed |
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| Format |
application/pdf
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| Identifier |
http://neist.csircentral.net/120/1/2568_CatComm9_5p.709%2D14.pdf
Das , Sharma S and Hazarika, P and Konwar, D (2008) A simple, green and one-pot four-component synthesis of 1,4-dihydropyridines and their aromatization. Catalysis Communications, 9 (5). pp. 709-714. |
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| Relation |
http://neist.csircentral.net/120/
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