Expandase-like activity mediated cell-free conversion of ampicillin to cephalexin by Streptomyces sp. DRS I
IR@NEIST: CSIR-North East Institute of Science and Technology, Jorhat
View Archive Info| Field | Value | |
| Title |
Expandase-like activity mediated cell-free conversion
of ampicillin to cephalexin by Streptomyces sp. DRS I
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| Creator |
Thakur, D
Roy, M K Bora, T C |
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| Subject |
Biotechnology
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| Description |
Cell-free extracts of Streptomyces sp.
DRS I converted ampicillin to cephalexin, presumably
due to the activity of the enzyme, expandase. The
extract was fractionated and characterized by colorimetric
and chromatographic measurements coupled
with disc-agar diffusion bioassay against an ampicillinresistant,
cephalexin-sensitive E. coli strain. Though
expandase could not be identified, the presence of
a hitherto unreported expandase in Streptomyces sp.
DRS I is suggested.
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| Publisher |
Springer
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| Date |
2009
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| Type |
Article
PeerReviewed |
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| Format |
application/pdf
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| Identifier |
http://neist.csircentral.net/175/1/2698_Biotechnol_Lett_2009_.pdf
Thakur, D and Roy, M K and Bora, T C (2009) Expandase-like activity mediated cell-free conversion of ampicillin to cephalexin by Streptomyces sp. DRS I. Biotechnology Letters, 31. pp. 1059-1064. |
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| Relation |
http://neist.csircentral.net/175/
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