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Highly Regio- and Stereoselective One-Pot Synthesis of Carbohydrate-Based Butyrolactones

IR@IIIM: CSIR-Indian Institute of Integrative Medicine, Jammu

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Title Highly Regio- and Stereoselective One-Pot Synthesis of Carbohydrate-Based Butyrolactones
 
Creator Yousuf, Syed Khalid
Mukherjee, Debaraj
L, Mallikharjunrao
Taneja, Subhash C.
 
Subject Chemical Sciences
 
Description The use of manganese(III) acetate allows the direct synthesis of diverse arrays of [4.3.0] bicyclic carbohydrate-based γ-lactone building blocks from glycals. A mechanism to explain the high regio- and stereoselectivity is proposed. The new reaction has the potential to generate libraries for biological screening.
 
Date 2011
 
Type Article
PeerReviewed
 
Format application/pdf
 
Identifier http://iiim.csircentral.net/378/1/10.1021ol102723c.pdf
Yousuf, Syed Khalid and Mukherjee, Debaraj and L, Mallikharjunrao and Taneja, Subhash C. (2011) Highly Regio- and Stereoselective One-Pot Synthesis of Carbohydrate-Based Butyrolactones. Organic Letters, 13 (4). pp. 576-579. ISSN 1523-7060
 
Relation http://dx.doi.org/10.1021/ol102723c
http://iiim.csircentral.net/378/