The Effect of Surface-Coupled Antigen of Liposomes in Immunopotentiation
IR@IICB: CSIR-Indian Institute of Chemical Biology, Kolkata
View Archive Info| Field | Value | |
| Title |
The Effect of Surface-Coupled Antigen of Liposomes in Immunopotentiation
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| Creator |
Ali, Nahid
Bachhawat, Bimal K |
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| Subject |
Infectious Diseases and Immunology
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| Description |
The effect of surface coupled antigens of liposomes
on the immunological response has been investigated.
Lysozyme was covalently coupled to
neutral and positively charged liposomes using
glutaraldehyde. Subcutaneous administration of
these preparations stimulated a significant antibody
response higher than that elicited by the antigen
entrapped in neutral liposomes. Immunization
by liposomal antigens together with complete
Freund’s adjuvant resulted in strong immune
responses, highest with the antigen coupled to neutral
and positively charged liposomes followed by
the antigen entrapped in neutral liposomes.
Primary and secondary immunization with lysozyme,
both entrapped and coupled to liposomes,
evoked an IgG response.
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| Publisher |
Elsevier
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| Date |
1987
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| Type |
Article
PeerReviewed |
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| Format |
application/pdf
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| Identifier |
http://www.eprints.iicb.res.in/1431/1/IMMUNOLOGY_LETTERS___15(_1)_45%2D51[44].pdf
Ali, Nahid and Bachhawat, Bimal K (1987) The Effect of Surface-Coupled Antigen of Liposomes in Immunopotentiation. Immunology Letters, 15 (1). pp. 45-51. |
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| Relation |
http://dx.doi.org/10.1016/0165-2478(87)90075-7
http://www.eprints.iicb.res.in/1431/ |
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