Antioxidant and antibacterial activities of bark extracts from Commiphora berryi and Commiphora caudata
IR@IICB: CSIR-Indian Institute of Chemical Biology, Kolkata
View Archive Info| Field | Value | |
| Title |
Antioxidant and antibacterial activities of bark extracts from Commiphora berryi and Commiphora caudata
|
|
| Creator |
Kumari, Ramesh
Meyyappan, Arumugam Nandi, Debkumar Agrawal, Bikram Keshari Acharya Chowdhury, Avik Selvamani, Palanisamy Latha, Subbaiah Giri, V S Mukherjee, Joydeep Bandyopadhyay, Santu Jaisankar , P |
|
| Subject |
Chemistry
Infectious Diseases and Immunology |
|
| Description |
This study investigates the in vitro antioxidant and antimicrobial activities
of eight extracts obtained from the dried barks of Commiphora berryi and
Commiphora caudata (Burseraceae). The radical scavenging activity was
assessed by 1,1-diphenyl-2-picryl hydrazyl (DPPH) and nitric oxide assays.
The methanolic extracts of C. berryi and C. caudata showed significant
DPPH radical scavenging activity, with IC50 values of 26.92 and
21.16 mgmL�1, respectively, and low radical scavenging activity against
the nitric oxide assay. The antimicrobial activity of the plants was tested
against the Gram-positive and Gram-negative bacteria. The ethyl acetate,
chloroform and petroleum ether extracts of C. berryi showed good
antibacterial activity against Pseudomonas aeruginosa, with a minimum
inhibitory concentration (MIC) of 0.26 mgmL�1, whereas the ethyl acetate
and methanol extracts of C. caudata showed moderate antimicrobial
activity with an MIC of more than 2.0 mgmL�1 against P. aeruginosa
compared to the petroleum ether and chloroform extracts, which showed
an MIC of 1.1 mgmL�1. The methanolic extracts of C. berryi and C.
caudata also showed moderate cytotoxic activity against a human mammary
carcinoma cell line (MCF-7), with values IC50 of 82.6 and
88.4 mgmL�1, respectively
|
|
| Publisher |
Taylor & Francis
|
|
| Date |
2011
|
|
| Type |
Article
PeerReviewed |
|
| Format |
application/pdf
|
|
| Identifier |
http://www.eprints.iicb.res.in/1632/1/Natural_product_research%2C_2011.pdf
Kumari, Ramesh and Meyyappan, Arumugam and Nandi, Debkumar and Agrawal, Bikram Keshari and Acharya Chowdhury, Avik and Selvamani, Palanisamy and Latha, Subbaiah and Giri, V S and Mukherjee, Joydeep and Bandyopadhyay, Santu and Jaisankar , P (2011) Antioxidant and antibacterial activities of bark extracts from Commiphora berryi and Commiphora caudata. Natural Product Research, 25 (15). pp. 1454-1462. ISSN 1478-6419 |
|
| Relation |
http://dx.doi.org/10.1080/14786411003752052
http://www.eprints.iicb.res.in/1632/ |
|