Chalcones as promising pesticidal agents against diamondback moth (Plutella xylostella): microwave-assisted synthesis and structure–activity relationship
IR@IHBT: CSIR-Institute of Himalayan Bioresource Technology, Palampur
View Archive Info| Field | Value | |
| Title |
Chalcones as promising pesticidal agents against diamondback
moth (Plutella xylostella): microwave-assisted synthesis
and structure–activity relationship
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| Creator |
Kumar , Rakesh
Sharma , Prabha Shard , Amit Tewary, D K Nadda , Gireesh Sinha, Arun K |
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| Subject |
Natural Product Chemistry
Pest and Pesticides |
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| Description |
A series of chalcones (A–CH=CH–CO–B)
were synthesized under microwave irradiation, and for the
first time their pesticidal activity against diamondback
moth (Plutella xylostella) was evaluated to identify the
promising lead structures. The structure–activity relationship
(SAR) analysis revealed that electron-withdrawing
substituents on ring A of chalcone provided good pesticidal
agents, whereas, ring B can bear either electron-withdrawing
or electron-releasing substituents. Moreover,
compound 22 having para-Cl substitution on ring A as well
on ring B showed maximum activity with LC50 value of
170.24 lg mL-1.
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| Date |
2012
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| Type |
Article
PeerReviewed |
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| Format |
application/pdf
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| Identifier |
http://ihbt.csircentral.net/1204/1/7_Chalcones_as_promising.pdf
Kumar , Rakesh and Sharma , Prabha and Shard , Amit and Tewary, D K and Nadda , Gireesh and Sinha, Arun K (2012) Chalcones as promising pesticidal agents against diamondback moth (Plutella xylostella): microwave-assisted synthesis and structure–activity relationship. Medicinal Chemistry Research, 21. pp. 922-931. |
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| Relation |
http://ihbt.csircentral.net/1204/
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