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Naturally occurring himachalenes to benzocycloheptene amino vinyl bromide derivatives: as antidepressant molecules

IR@IHBT: CSIR-Institute of Himalayan Bioresource Technology, Palampur

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Title Naturally occurring himachalenes to benzocycloheptene amino vinyl bromide derivatives: as antidepressant molecules
 
Creator Chaudhary, A
Das, Pralay
Mishra, Awanish
Kaur, Pushpinder
Singh , Bikram
Goel, R K
 
Subject Natural Product Chemistry
 
Description A new series of benzocycloheptene amino vinyl bromide derivatives (9a–9m) were synthesized from isomeric mixture of himachalenes through two-step synthesis. The unusual structure of benzocycloheptene amino vinyl bromide derivative (9a) was confirmed by NMRand X-ray crystallography analyses. The newly synthesized amino vinyl bromide derivatives of benzocycloheptene were further evaluated for their antidepressant activities. The compound 9c had shown significant reduction in the immobility period.
 
Date 2012
 
Type Article
PeerReviewed
 
Format application/pdf
 
Identifier http://ihbt.csircentral.net/1224/1/29_Naturally_occurring.pdf
Chaudhary, A and Das, Pralay and Mishra, Awanish and Kaur, Pushpinder and Singh , Bikram and Goel, R K (2012) Naturally occurring himachalenes to benzocycloheptene amino vinyl bromide derivatives: as antidepressant molecules. Molecular Diversity, 16. pp. 357-366.
 
Relation http://ihbt.csircentral.net/1224/