CSIR Central

A PROCESS FOR THE PREPARATION OF PHARMACOLOGICALLY ACTIVE ά-ASARONE FROM TOXIC β-ASARONE RICH ACORUS CALAMUS OIL"

IR@IHBT: CSIR-Institute of Himalayan Bioresource Technology, Palampur

View Archive Info
 
 
Field Value
 
Title A PROCESS FOR THE PREPARATION OF PHARMACOLOGICALLY ACTIVE ά-ASARONE FROM TOXIC β-ASARONE RICH ACORUS CALAMUS OIL"
 
Creator Sinha, Arun K
Joshi, B P
Acharya , R
 
Subject Plant sciences
Natural Product Chemistry
 
Description The present invention relates to a process for the preparation of high purity and yield aasarone, trans 2,4,5-trimethoxy cinnamaldehyde, 2,4,5-trimethoxy-phenyl propionone, from p-asarone or P-asarone rich Acorus calamus oil containing a and y-asarone by hydrogenating, followed by treatment with DDQ with or without solid support of silica gel or alumina in dry organic solvent and a-asarone can also be obtained by treating the hydrogenated product of P-asarone or P-asarone rich Acorus calamus with DDQ in an aqueous organic solvent to obtain an intermediate 2,4,5-trimethoxy phenyl propionone, which in turn is reduced with sodiumborohydride to obtain the corresponding 2,4,5- trimethoxy-phenyl propanol and followed by final treatment with a dehydrating agent
 
Date 2007-10-12
 
Type Patent
NonPeerReviewed
 
Format application/pdf
 
Identifier http://ihbt.csircentral.net/1035/1/India_36.pdf
csir, ihbt (2007) A PROCESS FOR THE PREPARATION OF PHARMACOLOGICALLY ACTIVE ά-ASARONE FROM TOXIC β-ASARONE RICH ACORUS CALAMUS OIL". 382/DEL/2002 (199804).
 
Relation http://ihbt.csircentral.net/1035/