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Presence of Exposed Phospholipids in the Outer Membrane of Vibrio Cholerae

IR@IICB: CSIR-Indian Institute of Chemical Biology, Kolkata

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Title Presence of Exposed Phospholipids in the Outer Membrane of Vibrio Cholerae
 
Creator Paul, Saptarshi
Chaudhuri, Keya
Cahtterjee, Anadi Nath
Das, Jyotirmoy
 
Subject Infectious Diseases and Immunology
 
Description Vibrio choferae 569B was found to be highly sensitive to a wide range of chemicals, particularly hydrophobic compounds and neutral and anionic detergents. The phospholipid profile of the outer membrane was similar to that reported for other Gram-negative bacteria. The lipopolysaccharide (LPS) contained 0-antigenic sugars and exhibited heterogeneity. In addition, the LPS moiety was characterized by a relatively low negative charge. Analysis by topological probes revealed the presence of a significant amount of exposed phospholipids in the outer membrane. The reduced negative charge of LPS molecules and the exposed phospholipids present in the outer membrane could be important in the increased permeation of exogenous compounds in V. choferae
 
Date 1992
 
Type Article
PeerReviewed
 
Format application/pdf
 
Identifier http://www.eprints.iicb.res.in/1792/1/JOURNAL_OF_GENERAL_MICROBIOLOGY__138__755%2D761___Part_Part_4_;1992[42].pdf
Paul, Saptarshi and Chaudhuri, Keya and Cahtterjee, Anadi Nath and Das, Jyotirmoy (1992) Presence of Exposed Phospholipids in the Outer Membrane of Vibrio Cholerae. Journal of General Microbiology, 138 (4). pp. 755-761.
 
Relation http://dx.doi.org/10.1099/00221287-138-4-755
http://www.eprints.iicb.res.in/1792/