Antidyslipidemic and antioxidant activity of the constituents isolated from the leaves of Calophyllum inophyllum
IR@CDRI: CSIR-Central Drug Research Institute, Lucknow
View Archive Info| Field | Value | |
| Creator |
Prasad, Janki
Shrivastava, Atul Khanna, A K Bhatia, G Awasthi, S K Narender, T |
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| Date |
2013-03-06T06:19:51Z
2013-03-06T06:19:51Z 2012 |
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| Identifier |
Phytomedicine 2012, 19 (14), 1245–1249
http://hdl.handle.net/123456789/1006 |
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| Description |
In continuation of our drug discovery program on Indian medicinal plants, we isolated bioactive compounds (1-5) from the leaves of Calophyllum inophyllum and evaluated their antidyslipidemic activity in triton induced hyperlipidemia model. The calophyllic acid (1A) and isocalophyllic acid (1B) mixture, canophyllic acid (4) and amentoflavone (5) showed dose dependent lipid lowering activity in in-vivo experiments. The compounds 1A + 1B mixture and 3 also showed good in-vitro antioxidant activity.
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177081 bytes
application/pdf |
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| Language |
en
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| Relation |
CDRI Communication No. 8322
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| Subject |
Calophyllum inophyllum
Antidyslipidemic activity Triton model Antioxidant activity |
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| Title |
Antidyslipidemic and antioxidant activity of the constituents isolated from the leaves of Calophyllum inophyllum
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| Type |
Article
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