pEapfefricient Synthesis of Imidazole-Fused Benzodiazepines Using Palladium- Catalyzed Intramolecular C–N Bond Formation Reaction
IR@IICB: CSIR-Indian Institute of Chemical Biology, Kolkata
View Archive Info| Field | Value | |
| Title |
pEapfefricient Synthesis of Imidazole-Fused Benzodiazepines Using Palladium- Catalyzed Intramolecular C–N Bond Formation Reaction
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| Creator |
Mitra, Sudipta
Darira, Heena Chattopadhyay, Partha |
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| Subject |
Chemistry
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| Description |
An efficient three-step synthetic route to imidazolefused
benzodiazepines from imidazole-2-carbaldehyde is described.
Application of intramolecular Buchwald–Hartwig cycloamination
reaction in the final step is shown to be a convenient
method for the synthesis of fused seven-membered diazacycles. The
reactions proceeded smoothly with both aliphatic and aromatic
amines.
Key words: palladium, catalysis, amination, cyclization, benzodiazepine
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| Publisher |
Advanced online publication
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| Date |
2013
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| Type |
Article
PeerReviewed |
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| Format |
application/pdf
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| Identifier |
http://www.eprints.iicb.res.in/1864/1/SYNTHESIS%2DSTUTTGART___45(_Issue_1)85%2D92_;2013[38].pdf
Mitra, Sudipta and Darira, Heena and Chattopadhyay, Partha (2013) pEapfefricient Synthesis of Imidazole-Fused Benzodiazepines Using Palladium- Catalyzed Intramolecular C–N Bond Formation Reaction. SYNTHESIS, 45 (1). pp. 85-92. |
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| Relation |
http://dx.doi.org/10.1055/s-0032-1316828
http://www.eprints.iicb.res.in/1864/ |
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