Head and Neck Cancer: Role of DNA Repair Gene Polymorphisms and Mapping Altered Genomic Regions
IR@IICB: CSIR-Indian Institute of Chemical Biology, Kolkata
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| Title |
Head and Neck Cancer: Role of DNA Repair Gene Polymorphisms and Mapping Altered Genomic Regions
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| Creator |
Mondal, Pinaki
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| Subject |
Molecular & Human Genetics
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| Description |
Cancer is a disease of uncontrolled cell division that occurs in different parts of the body. The uncontrolled growth may sometime stop and became benign or may spread to other parts of the body by a process called metastasis. Over the years it became clear that an underlying genetic and epigenetic defect is responsible for such occasional abnormal growth of cells in an individual. At the gross level such genetic abnormality was first reflected as chromosomal aneuploidy (Lengauer, et al., 1997). More than 100 years ago, Theodor Heinrich Boveri, German biologist who postulated the association between abnormal growth of sea-urchin eggs and ‘wrong’ chromosomal complement in a cell (Boveri, 1902). Until now, although with the aid of hundreds of modern technologies, scientists have identified a large number of such abnormalities, more details about this complex disease is still unclear.
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| Date |
2013
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| Type |
Thesis
NonPeerReviewed |
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| Format |
application/pdf
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| Identifier |
http://www.eprints.iicb.res.in/1874/1/Main.pdf
Mondal, Pinaki (2013) Head and Neck Cancer: Role of DNA Repair Gene Polymorphisms and Mapping Altered Genomic Regions. PhD thesis, Calcutta University. |
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| Relation |
http://www.eprints.iicb.res.in/1874/
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