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Liquid membrane phenomena in antiarrhythmic action.

IR@AMPRI: CSIR-Advanced Materials and Processes Research Institute, Bhopal

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Title Liquid membrane phenomena in antiarrhythmic action.
 
Creator Dr., R.C. Srivastava
Dr., R K Sharma
Dr., C.V.S. Subrahmanyam
Dr., S.B. Bhise
 
Subject Rural Technology Development and Dissemination
 
Description Antiarrhythmic drugs have been shown to generate liquid membranes in series with a supporting membrane. Transport of sodium ions across the liquid membrane generated by these drugs has been studied. The data indicate that the transport of sodium ions is impeded in presence of the liquid membranes. Relevance of this observation to antiarrhythmic action has been discussed. Four structurally dissimilar antiarrhythmic drugs, namely quinidine, disopyramide, procainamide and propranolol, have been investigated.
 
Date 1986
 
Type Article
PeerReviewed
 
Identifier Dr., R.C. Srivastava and Dr., R K Sharma and Dr., C.V.S. Subrahmanyam and Dr., S.B. Bhise (1986) Liquid membrane phenomena in antiarrhythmic action. International Journal of Pharmaceutics, 28. pp. 145-149.
 
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