Interleukin 2 enhances natural killing of varicella-zoster virus-infected targets
IR@IICB: CSIR-Indian Institute of Chemical Biology, Kolkata
View Archive Info| Field | Value | |
| Title |
Interleukin 2 enhances natural killing of varicella-zoster virus-infected targets
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| Creator |
Ito , M
Bandyopadhyay , Santu Matsumoto-Kobayashi, M Clark, S C Miller , Deborah Starr, S E |
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| Subject |
Infectious Diseases and Immunology
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| Description |
Preincubation of peripheral blood non-adherent mononuclear cells with purified or
recombinant interleukin 2 (IL-2) significantly enhanced natural killer (NK) activity
against uninfected and varicella-zoster virus (VZV)-infected targets, while antibodydependent
cellular cytotoxicity (ADCC) against VZV-infected targets was not increased.
Preincubation of effector cells with IL-2 had no effect on conjugate formation, but lysis of
both targets was increased in single cell assays. IL-2-enhanced NK against VZV-infected
targets was independent of gamma-interferon (y-IFN) production.
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| Date |
1986
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| Type |
Article
PeerReviewed |
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| Format |
application/pdf
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| Identifier |
http://www.eprints.iicb.res.in/1902/1/Clin_Exp_Immunol.__65%2C_182%2D189;1986.pdf
Ito , M and Bandyopadhyay , Santu and Matsumoto-Kobayashi, M and Clark, S C and Miller , Deborah and Starr, S E (1986) Interleukin 2 enhances natural killing of varicella-zoster virus-infected targets. Clinical experimental Immunology, 65. pp. 182-189. |
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| Relation |
http://www.eprints.iicb.res.in/1902/
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