3,6-Dibenzoxyl-l,2-pyridazine: A new versatile benzoyl transferring agent for NH<sub>2</sub>, -OH and -SH benzoylations
IR@NISCAIR: CSIR-NISCAIR, New Delhi - ONLINE PERIODICALS REPOSITORY (NOPR)
View Archive Info| Field | Value | |
| Creator |
Mashraqui, Sabir Hussain
Shivaji, Jadhav Latika |
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| Date |
2013-09-20T05:12:32Z
2013-09-20T05:12:32Z 2004-05 |
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| Identifier |
0975-0983(Online); 0376-4699(Print)
http://hdl.handle.net/123456789/21272 |
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| Description |
927-935
A newly synthesized 3,6-dibenzoxyl- 1,2-pyridazinc <b>3</b> has been investigated for its potential to transfer the benzoyl group to various organic substrates carrying -NH<sub>2</sub>, - OH and - SH groups. The benzoyl transfer is fairly general in scope, occurs under convenient conditions and provides good to excellent yields of benzoylated products. Moreover, by choosing proper conditions, it is possible to achieve chemoselective benzoylation in bi-functional molecules . For instance, N-benzoylation of aromatic amines can be selectively accomplished over that of aliphatic amines and vice versa by manipulating reaction conditions. Selective N- or O-benzoylation in aminophenols is also possible. Although, not studied in detail, we find that dibenzoate <b>3</b> can also be used to effect C-benzoylation of reactive phenols and ketones, as exemplified by the C-benzoylation of resorcinol and acetophenone, respectively. Dibenzoate <b>3</b>, besides being a crystalline, easy to handle, solid possesses twice the potential as an acyl carrier compared to the other known acyl carriers. These features make <b>3 </b>as an attractive choice for many applications pertaining to benzoyl transfer reactions. |
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| Language |
en_US
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| Publisher |
NISCAIR-CSIR, India
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| Relation |
<span style="font-size:12.0pt;line-height:115%; font-family:"Times New Roman","serif";mso-bidi-font-weight:bold" lang="EN-IN">Inl Cl.<sup>7</sup> C 07D 237/00 </span>
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| Rights |
<img src='http://nopr.niscair.res.in/image/cc-license-sml.png'> <a href='http://creativecommons.org/licenses/by-nc-nd/2.5/in' target='_blank'>CC Attribution-Noncommercial-No Derivative Works 2.5 India</a>
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| Source |
IJC-B Vol.43B(05) [May 2004]
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| Title |
3,6-Dibenzoxyl-l,2-pyridazine: A new versatile benzoyl transferring agent for NH<sub>2</sub>, -OH and -SH benzoylations
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| Type |
Article
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