Facile Synthesis of [1,2,3]-Triazole-Fused Isoindolines, Tetrahydroisoquinolines, Benzoazepines and Benzoazocines by Palladium-Copper Catalysed Heterocyclisation
IR@IICB: CSIR-Indian Institute of Chemical Biology, Kolkata
View Archive Info| Field | Value | |
| Title |
Facile Synthesis of [1,2,3]-Triazole-Fused Isoindolines, Tetrahydroisoquinolines, Benzoazepines and Benzoazocines by Palladium-Copper Catalysed Heterocyclisation
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| Creator |
Brahma, Kaushik
Achari, Basudeb Chowdhury, Chinmay |
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| Subject |
Chemistry
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| Description |
An elegant method for the synthesis of 1,2,3-triazoles
fused with five-, six-, seven- and eight-membered benzoheterocycles, including isoindoline, tetrahydroisoquinoline, benzoazepine and benzoazocine, has been developed via palladium-copper catalysed reactions in one-pot. The broad scope of this reaction was illustrated
by effecting bis-heteroannulations, synthesis of uracil
derivatives of biological interest, and employment of acetylene gas as an inexpensive substrate. The reactions are experimentally simple and utilise easily accessible substrates of different types
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| Date |
2013
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| Type |
Article
PeerReviewed |
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| Format |
application/pdf
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| Identifier |
http://www.eprints.iicb.res.in/1956/1/SYNTHESIS%2DSTUTTGART__Volume_45___Issue_4___Pages_545%2D555;2013.pdf
Brahma, Kaushik and Achari, Basudeb and Chowdhury, Chinmay (2013) Facile Synthesis of [1,2,3]-Triazole-Fused Isoindolines, Tetrahydroisoquinolines, Benzoazepines and Benzoazocines by Palladium-Copper Catalysed Heterocyclisation. Synthesis, 45 (4). pp. 545-555. |
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| Relation |
http://dx.doi.org/ 10.1055/s-0032-1316839;
http://www.eprints.iicb.res.in/1956/ |
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