Tricarbonyltechnetium(I) and tricarbonylrhenium(I) complexes of amino acids: crystal and molecular structure of a novel cyclic dimeric Re(CO)3-amino acid complex comprised of the OON donor atom set of the tridentate ligand
IR@IICB: CSIR-Indian Institute of Chemical Biology, Kolkata
View Archive Info| Field | Value | |
| Title |
Tricarbonyltechnetium(I) and tricarbonylrhenium(I)
complexes of amino acids: crystal and molecular
structure of a novel cyclic dimeric Re(CO)3-amino acid
complex comprised of the OON donor atom set of the
tridentate ligand
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| Creator |
Nayak, Dipak Kumar
Halder, Kamal Krishna Baishya, Rinku Sen, Tuhinadri Mitra, Partha Chatterjee Debnath, Mita |
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| Subject |
Infectious Diseases and Immunology
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| Description |
Radiolabeled complexes of monoamino polycarboxylic, polyamino monocarboxylic and thiol containing
amino acid ligands were prepared from a fac-[99mTc(CO)3(H2O)3]+ precursor.The overall radiochemical
yield was 94–98%. The complexes exhibited substantial in vitro and in vivo stability. The corresponding Re(I)
complexes of the ligands DAPA, Asp and CysH were prepared and characterized by means of IR, NMR, and
MS spectroscopic studies, as well as X-ray crystallography (for those containing D,L-DAPA and D,L-Asp). The
rhenium complexes have been structurally correlated with the technetium complexes by means of HPLC
studies. The reaction of Re(CO)5Cl with D,L-Asp in presence of triethylamine led to the formation of a new
class of cyclic dimeric complexes formed by the OON donor atom set of the tridentate ligands. The amino
carboxylate ligand system formed well defined complexes with a fac-[M(CO)3(H2O)3]+ core and shows
good promise in 99mTc(CO)3 tracer development
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| Publisher |
Royal Society of Chemistry
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| Date |
2013
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| Type |
Article
PeerReviewed |
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| Format |
application/pdf
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| Identifier |
http://www.eprints.iicb.res.in/1960/1/DALTON_TRANSACTIONS__Volume_42__(37)___Pages_13565%2D13575;2013[127].pdf
Nayak, Dipak Kumar and Halder, Kamal Krishna and Baishya, Rinku and Sen, Tuhinadri and Mitra, Partha and Chatterjee Debnath, Mita (2013) Tricarbonyltechnetium(I) and tricarbonylrhenium(I) complexes of amino acids: crystal and molecular structure of a novel cyclic dimeric Re(CO)3-amino acid complex comprised of the OON donor atom set of the tridentate ligand. Dalton Transactions, 42 (37). pp. 13565-13575. |
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| Relation |
http://dx.doi.org/10.1039/c3dt50928a
http://www.eprints.iicb.res.in/1960/ |
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