Antioxidant and nitric oxide synthase activation properties of <i>Ganoderma</i> <i>applanatum</i>
IR@NISCAIR: CSIR-NISCAIR, New Delhi - ONLINE PERIODICALS REPOSITORY (NOPR)
View Archive Info| Field | Value | |
| Creator |
Acharya, Krishnendu
Yonzone, Parinita Rai, Manjula Acharya, Rupa |
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| Date |
2013-11-11T11:28:32Z
2013-11-11T11:28:32Z 2005-10 |
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| Identifier |
0975-1009 (Online); 0019-5189 (Print)
http://hdl.handle.net/123456789/23263 |
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| Description |
926-929
<i>In vitro </i>evaluation of antioxidant activities of <i>Ganoderma</i> <i>applanatum</i> showed significant inhibition of lipid peroxidation,<i> </i>and potent hydroxyl radical scavenging activity when compared<i> </i>with standard drug catechin. IC<sub>50</sub> values of crude, boiled and<i> </i>ethanolic extracts of <i>G</i>. <i>applanatum </i>were 604.8, 624 and 267<i> μ</i>g/ml,<i> </i>respectively in case of hydroxyl radical scavenging<i> </i>activity, and 441, 520.5 and 166.16 <i>μ</i>g/ml,<i> </i>respectively in case of<i> </i>lipid peroxidation. Furthermore, crude, boiled and ethanoiic<i> </i>extracts also increased significantly nitric oxide production<i> </i>(156.67, 121.88 and 742 pmole/mg dry wt/hr, respectively) over the control. The results of present investigation revealed that <i>G</i>. <i>applanatum </i>have potential therapeutic use. |
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| Language |
en_US
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| Publisher |
NISCAIR-CSIR, India
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| Rights |
<img src='http://nopr.niscair.res.in/image/cc-license-sml.png'> <a href='http://creativecommons.org/licenses/by-nc-nd/2.5/in' target='_blank'>CC Attribution-Noncommercial-No Derivative Works 2.5 India</a>
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| Source |
IJEB Vol.43(10) [October 2005]
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| Subject |
Antioxidant activity
<i>Ganoderma applanatum</i> Nitric oxide synthase |
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| Title |
Antioxidant and nitric oxide synthase activation properties of <i>Ganoderma</i> <i>applanatum</i>
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| Type |
Article
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