Current trends in evaluation of sperm function: <i>In vitro </i>selection and manipulation of male gametes for assisted conception
IR@NISCAIR: CSIR-NISCAIR, New Delhi - ONLINE PERIODICALS REPOSITORY (NOPR)
View Archive Info| Field | Value | |
| Creator |
Varghese, Alex C
Sinha, Barnali Bhattacharyya, Asok K |
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| Date |
2013-11-11T11:43:17Z
2013-11-11T11:43:17Z 2005-11 |
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| Identifier |
0975-1009 (Online); 0019-5189 (Print)
http://hdl.handle.net/123456789/23271 |
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| Description |
1023-1031
With increasing medical utilization of assisted reproductive technology (ART), scientists and clinicians have been able to study extensively multiple cell functions operating synchronously and flawlessly during the events preceding, before and after fertilization. Critical evaluation of the functional status of spermatozoa for <i>in vitro </i>techniques such as sperm-mucus interaction, acrosome reaction status, sperm-zona pellucida binding and penetration tests, hyaluronic acid binding assay, and computer assisted semen analysis etc. can direct a male partner of an infertile couple to more aggressive forms of treatments. <i>In vitro </i>selection of functionally competent sperm cells is a pre-requisite for successful outcome in <i>in vitro </i>fertilization or in intracytoplasmic sperm injection (ICSI). Direct injections of acrosome-intact spermatozoa into oocyte during ICSI bypassing the normal events of sperm oocyte interaction and fusion events have raised concerns with regard to fertilization abnormalities and genetic issues. The present communication briefly reviews the sperm function tests with emphasis on its correlation with fertility outcome, and the currently employed sperm selection and manipulation procedures which may have implications in assisted conception programs. |
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| Language |
en_US
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| Publisher |
NISCAIR-CSIR, India
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| Rights |
<img src='http://nopr.niscair.res.in/image/cc-license-sml.png'> <a href='http://creativecommons.org/licenses/by-nc-nd/2.5/in' target='_blank'>CC Attribution-Noncommercial-No Derivative Works 2.5 India</a>
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| Source |
IJEB Vol.43(11) [November 2005]
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| Subject |
Assisted conception
Male gamete Spermatozoa Sperm function |
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| Title |
Current trends in evaluation of sperm function: <i>In vitro </i>selection and manipulation of male gametes for assisted conception
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| Type |
Article
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