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Molecular Study of Micrornamediated Regulation of Mitosis and its Impact on Oral Carcinogenesis

IR@IICB: CSIR-Indian Institute of Chemical Biology, Kolkata

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Title Molecular Study of Micrornamediated Regulation of Mitosis and its Impact on Oral Carcinogenesis
 
Creator Bhattacharya, Sumana
 
Subject Cancer Biology and Inflammatory Disorder Division
 
Description Cancer is a complex disorder, a group of more than 100 diseases that develop across time and involve the uncontrolled proliferation of the body's cells. Although cancer can develop in virtually any of the body's tissues, and each type of cancer has its unique features, the basic processes that produce cancer are quite similar in all forms of the disorder [1]. In this multistep process, cells acquire a series of mutations that eventually lead to unrestrained cell growth and division, inhibition of cell differentiation, and evasion of cell death. These cells break free from the normal restraints on cell division and begin to follow their own agenda for proliferation (Fig. 1). A tumour, formed of these abnormal cells may remain within the tissue in which it originated (in situ cancer), or it may begin to invade nearby tissues (invasive cancer). An invasive tumour is said to be malignant, and cells shed into the blood or lymph from a malignant tumour are likely to establish new tumours (metastases) throughout the body.
 
Date 2013
 
Type Thesis
NonPeerReviewed
 
Format application/pdf
 
Identifier http://www.eprints.iicb.res.in/1985/1/Thesis.pdf
Bhattacharya, Sumana (2013) Molecular Study of Micrornamediated Regulation of Mitosis and its Impact on Oral Carcinogenesis. PhD thesis, Calcutta University.
 
Relation http://www.eprints.iicb.res.in/1985/