Substituent-guided switch between C-H activation and decarboxylative cross-coupling during Palladium/ Copper-catalyzed cascade reaction of 2-aminobenzoates with 2-haloarylaldehydes
IR@CDRI: CSIR-Central Drug Research Institute, Lucknow
View Archive Info| Field | Value | |
| Creator |
Bhowmik, Subhendu
Pandey, Garima Batra, Sanjay |
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| Date |
2014-05-09T07:30:21Z
2014-05-09T07:30:21Z 2013 |
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| Identifier |
Chemistry A European Journal, 2013, 19, 10487 – 10491
http://hdl.handle.net/123456789/1218 |
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| Description |
Phenanthridines, pyrazole[4,3-c]quinolines and isocryptolepine are prepared in one-step from Pd/ Cu-catalyzed reaction between potassium 2-aminobenzoates and 2-haloarylaldehydes. Whereas the reactions of 2-aminobenzoates proceed via a cascade imination/ C-H functionalization, the reactions of 6-nitro-2-aminobenzoate ensues via tandem imination/ decarboxylative cross-coupling. Both sequences can be achieved with low catalyst loading and works over a broad substrate base.
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| Format |
364780 bytes
application/pdf |
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| Language |
en
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| Relation |
CSIR-CDRI Communication No. 8456
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| Subject |
Palladium
Copper Nitrogen heterocycles C-H activation decarboxylative cross coupling Domino |
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| Title |
Substituent-guided switch between C-H activation and decarboxylative cross-coupling during Palladium/ Copper-catalyzed cascade reaction of 2-aminobenzoates with 2-haloarylaldehydes
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| Type |
Article
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