Morita-Baylis-Hillman Approach toward Formal Total Synthesis of Tamiflu and Total Synthesis of Gabaculine§
IR@CDRI: CSIR-Central Drug Research Institute, Lucknow
View Archive Info| Field | Value | |
| Creator |
Bhowmik, Subhendu
Batra, Sanjay |
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| Date |
2014-07-10T10:57:36Z
2014-07-10T10:57:36Z 2013 |
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| Identifier |
European Journal of Organic Chemistry, 2013, 2013, (31), 7145–7151
http://hdl.handle.net/123456789/1306 |
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| Description |
A Morita-Baylis-Hillman reaction mediated approach to formal total synthesis of Oseltamivir and total synthesis of Gabaculine is described. The strategy involves enantiocontrolled preparation of Corey's intermediate in 22% yields starting from N-Boc L-serine methyl ester over 11 steps
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| Format |
258541 bytes
application/pdf |
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| Language |
en
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| Relation |
CSIR-CDRI Communication No. 8493.
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| Subject |
Oseltamivir
Morita-Baylis-Hillman Gabaculine Ring closing metathesis Serine |
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| Title |
Morita-Baylis-Hillman Approach toward Formal Total Synthesis of Tamiflu and Total Synthesis of Gabaculine§
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| Type |
Article
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