Tandem C-2 Functionalization-Intramolecular Azide-Alkyne 1,3-dipolar Cycloaddition Reaction: A Convenient Route to Highly Diversified 9H-benzo[b]pyrrolo [1,2-g][1,2,3]triazolo[1,5-d][1,4] diazepines
IR@CDRI: CSIR-Central Drug Research Institute, Lucknow
View Archive Info| Field | Value | |
| Creator |
Hussain, M K
Ansari, M I Kant, Ruchir Hajela, Kanchan |
|
| Date |
2014-08-01T10:16:33Z
2014-08-01T10:16:33Z 2014 |
|
| Identifier |
Organic Letters, 2014, 16 (2), 560–563
http://hdl.handle.net/123456789/1333 |
|
| Description |
An efficient diversity oriented synthetic approach to annulated 9H-benzo[b]pyrrolo[1,2-g][1,2,3]triazolo[1,5-d][1,4] diazepines has been developed using a Sc(OTf)3 catalyzed two component tandem C-2 functionalization-intramolecular azide-alkyne 1,3-dipolar cycloaddition reaction. The reaction shows high substrate tolerance and provides a library of fused heterocycles that may lead to novel biologically active compounds or drug lead molecules.
|
|
| Format |
211950 bytes
application/pdf |
|
| Language |
en
|
|
| Relation |
CSIR –CDRI Communication No. 8584
|
|
| Subject |
Tandem C-2 Functionalization
Cycloaddition Reaction Convenient Route Highly Diversified Diazepines |
|
| Title |
Tandem C-2 Functionalization-Intramolecular Azide-Alkyne 1,3-dipolar Cycloaddition Reaction: A Convenient Route to Highly Diversified 9H-benzo[b]pyrrolo [1,2-g][1,2,3]triazolo[1,5-d][1,4] diazepines
|
|
| Type |
Article
|
|