Cu(I)-Catalyzed Tandem Decarboxylative/C-H Activation Coupling reaction of Cyclic diketone, Proline and Alkyne: Synthesis of α-alkynylated pyrrolidine-oxyindoles
IR@CDRI: CSIR-Central Drug Research Institute, Lucknow
View Archive Info| Field | Value | |
| Creator |
Kumar, Atul
Kumar, Mukesh Gupta, L P Gupta, M K |
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| Date |
2014-08-04T11:41:06Z
2014-08-04T11:41:06Z 2014 |
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| Identifier |
RSC Advances, 2014, 4, 9412-9415
http://hdl.handle.net/123456789/1340 |
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| Description |
An efficient ligand/base and oxidant-free copper(I) catalyzed intermolecular direct alkynylation (IDA) strategy has been developed for the synthesis of α-alkynylated pyrrolidine-oxindole derivatives using cyclic diketones, amino acid and alkyne via tandem decarboxylative/C-H activation and reductive-amination strategy.
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| Format |
227624 bytes
application/pdf |
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| Language |
en
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| Relation |
CSIR-CDRI Communication No. 8610
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| Subject |
Oxidant-Free Copper
Cyclic Diketone Proline Alkyne Α-Alkynylated Pyrrolidine-Oxyindoles |
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| Title |
Cu(I)-Catalyzed Tandem Decarboxylative/C-H Activation Coupling reaction of Cyclic diketone, Proline and Alkyne: Synthesis of α-alkynylated pyrrolidine-oxyindoles
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| Type |
Article
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