Microwave Assisted [RuCl2(p-cymene)2]2 Catalyzed Regioselective Endo-Tandem Cyclization Involving Imine and Alkyne Activation: An Approach to benzo[4,5]imidazo[2,1-a]pyridine Scaffold
IR@CDRI: CSIR-Central Drug Research Institute, Lucknow
View Archive Info| Field | Value | |
| Creator |
Manna, S K
Panda, Gautam |
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| Date |
2014-08-12T04:54:39Z
2014-08-12T04:54:39Z 2014 |
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| Identifier |
RSC Advances, 2014, 4, 21032-21041
http://hdl.handle.net/123456789/1359 |
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| Description |
A microwave assisted efficient route to the synthesis of benzimidazole fused heterocycles through metal catalyzed endo-cyclization strategy involving imine and alkyne activation has been developed. In the presence of [RuCl2(p-cymene)2]2, a variety of 2-ethynyl aldehydes underwent cascade cyclization with substituted benzenediamines to afford the corresponding benzo[4,5]imidazo[2,1-a] pyridine scaffold in moderate to good yields.
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206495 bytes
application/pdf |
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| Language |
en
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| Relation |
CSIR-CDRI Communication No. 8658
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| Subject |
Imine
Alkyne |
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| Title |
Microwave Assisted [RuCl2(p-cymene)2]2 Catalyzed Regioselective Endo-Tandem Cyclization Involving Imine and Alkyne Activation: An Approach to benzo[4,5]imidazo[2,1-a]pyridine Scaffold
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Article
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