Palladium-Catalyzed Tandem Intramolecular Oxy/Amino-Palladation/Isocyanide Insertion: Synthesis of α-Benzofuranyl/Indolylacetamides
IR@CDRI: CSIR-Central Drug Research Institute, Lucknow
View Archive Info| Field | Value | |
| Creator |
Thirupathi, Nuligonda
Babu, M H Dwivedi, Vikas Reddy, M S |
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| Date |
2014-08-28T11:37:32Z
2014-08-28T11:37:32Z 2014 |
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| Identifier |
Organic Letters, 2014, 16 (11), 2908–2911
http://hdl.handle.net/123456789/1381 |
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| Description |
Anovel palladium-catalyzed approach to 2-benzofuranyl/indolylacetamides from 1-(o-hydroxy/aminophenyl)propargylic alcohols and isocyanides is described. The reaction proceeds through a cascade that includes oxy/amino-palladation, isocyanide insertion and 1,4-hydroxyl migration. No oxidant or ligand is needed to promote the cascade and the reactions are carried out in mild conditions to afford the products through high functional tolerance.
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| Format |
419923 bytes
application/pdf |
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| Language |
en
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| Relation |
CSIR-CDRI Communication No. 8688
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| Subject |
Palladium-Catalyzed
Tandem Intramolecular Oxy/Amino-Palladation/Isocyanide Insertion: Synthesis |
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| Title |
Palladium-Catalyzed Tandem Intramolecular Oxy/Amino-Palladation/Isocyanide Insertion: Synthesis of α-Benzofuranyl/Indolylacetamides
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| Type |
Article
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