Ugi Four-Component Reaction with Tandem Deprotection, Cyclization and Pictet–Spengler Reaction: A Concise Route to N-Fused Polycyclic Indolediketopiperazine Alkaloid Analogues
IR@CDRI: CSIR-Central Drug Research Institute, Lucknow
View Archive Info| Field | Value | |
| Creator |
Tyagi, Vikas
Khan, Shahnawaz Chauhan, P M S |
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| Date |
2014-09-11T11:33:21Z
2014-09-11T11:33:21Z 2013 |
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| Identifier |
Synlett, 2013, 24 (10), 1291-1297
http://hdl.handle.net/123456789/1402 |
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| Description |
Aza-fused polycyclic indolediketopiperazine alkaloids are of potential interest due to their broad range of biological activities. Traditionally, a number of methods have been reported to generate N-fused polycyclic indolediketopiperazine skeletons, but the development of novel, concise methods to modify its substitution pattern are strongly required. Herein, we have described the two-step formation of N-fused polycyclic indolediketopiperazine alkaloid analogues by the application of the Ugi 4-CR with tandem deprotection-cyclization/Pictet-Spengler reaction
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154987 bytes
application/pdf |
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| Language |
en
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| Relation |
CSIR-CDRI Communication No. 8434
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| Subject |
Indolediketopiperazine alkaloids
Ugi-multicomponent reaction Tandem reaction Deprotection-cyclization reactions Pictet-Spengler reaction |
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| Title |
Ugi Four-Component Reaction with Tandem Deprotection, Cyclization and Pictet–Spengler Reaction: A Concise Route to N-Fused Polycyclic Indolediketopiperazine Alkaloid Analogues
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| Type |
Article
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