Role of Apoptosis, Autophagy and Mitochondrial Dysfunction in Anti Leukemic Activities of Andrographolide and indole derivatives
IR@IICB: CSIR-Indian Institute of Chemical Biology, Kolkata
View Archive Info| Field | Value | |
| Title |
Role of Apoptosis, Autophagy and Mitochondrial Dysfunction in Anti Leukemic Activities of Andrographolide and indole derivatives
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| Creator |
Kumar, Deepak
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| Subject |
Cancer Biology and Inflammatory Disorder Division
Chemistry |
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| Description |
Cancer, the medical term of which is malignant neoplasm, is a class of disease in which a group of cells display uncontrolled growth (division beyond normal limits), invasion (intrusion on and destruction of adjacent tissues), and metastasis (spread to other locations in the body via lymph or blood). These three properties differentiate them from benign tumors which do not intrude into other regions (Merlo et al., 2006). According to the World Health Organization, cancer is the leading cause of death in developed countries and is second to cardiovascular diseases in developing countries. The total number of registered cases of cancer in the year 2010 was 979,786 of which 555,000 were cases of reported deaths (Takiar et al., 2010). International Agency for Research on Cancer estimates a whopping number of 16 million new cases of cancer by the year 2020. WHO also projects that cancer will soon replace ischemic heart disease as the overall leading cause of death worldwide (IARC press release, 2010-2020).
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| Date |
2014
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| Type |
Thesis
NonPeerReviewed |
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| Format |
application/pdf
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| Identifier |
http://www.eprints.iicb.res.in/2078/1/Thesis_Deepak_Kumar.pdf
Kumar, Deepak (2014) Role of Apoptosis, Autophagy and Mitochondrial Dysfunction in Anti Leukemic Activities of Andrographolide and indole derivatives. PhD thesis, Jadavpur University. |
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| Relation |
http://www.eprints.iicb.res.in/2078/
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