CSIR Central

Ameliorative Effect of Hibiscus rosa sinensis on Phenylhydrazine Induced Haematotoxicity

IR@CDRI: CSIR-Central Drug Research Institute, Lucknow

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Field Value
 
Creator Meena, A K
Patidar, Devendra
Singh, R K
 
Date 2015-03-20T05:09:19Z
2015-03-20T05:09:19Z
2014
 
Identifier International Journal of Innovative Research in Science, Engineering and Technology, 2014, 3(2), 8678-8683
http://hdl.handle.net/123456789/1431
 
Description This research work was focused on the haemoprotective activity of methanolic extract of Hibiscus rosa sinensis L. (HRS) flowers against phenylhydrazine induced haematotoxicity in Charles foster rats. Haemoprotective activity of methanolic extract of HRS flowers were estimated by using haematological parameter of Charles foster rats and it was evaluated with the help of MS9 fully automated haematology analyzer. The experimental activities for the methanolic extract of HRS exhibited statistically significant (p<0.005) haemoprotective activity against phenylhydrazine induced haematotoxicity in Charles foster rats. In conclusion, these observations provide evidence and possible mechanism of action for the haemoprotective activity of methanolic extract of HRS flowers. This activity of extract may be due to high phenolic and flavonoid contents.
 
Format 664202 bytes
application/pdf
 
Language en
 
Relation CSIR-CDRI Communication No. 8897
 
Subject Haemoprotective
Hibiscus rosa sinensis
Free Radical
Scavenging
Phenylhydrazine
Hemolytic anemia
 
Title Ameliorative Effect of Hibiscus rosa sinensis on Phenylhydrazine Induced Haematotoxicity
 
Type Article