Synthesis of 1,2,4- trioxepanes and 1,2,4-trioxanes via H2O2 me-diated reaction of tertiary carbinols
IR@CDRI: CSIR-Central Drug Research Institute, Lucknow
View Archive Info| Field | Value | |
| Creator |
Ravi, Makthala
Anand, Devireddy Maurya, Ranjani Chauhan, Parul Naikade, N K Shukla, S K Yadav, P P |
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| Date |
2013-10-04T07:47:52Z
2013-10-04T07:47:52Z 2013 |
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| Identifier |
Synlett, 2013, 24(2), 173-176
http://hdl.handle.net/123456789/1130 |
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| Description |
A facile and efficient method for the synthesis of 1, 2, 4-trioxepanes and 1, 2, 4-trioxanes from differ-ent carbinols having cyclopropyl and phenyl substituents have been explored. The corresponding hy-droxyhydroperoxides were synthesized from 30% H2O2 mediated reaction of carbinols in acidic condi-tions. This method gave an access to novel 6,6-diaryl substituted 1,2,4-trioxanes derived from benzilic acid.
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| Format |
117861 bytes
application/pdf |
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| Language |
en
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| Relation |
CDRI communication No. 8369
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| Subject |
1,2,4-trioxanes
1,2,4-trioxepanes Hydrogen peroxide, carbinols and antimalarial |
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| Title |
Synthesis of 1,2,4- trioxepanes and 1,2,4-trioxanes via H2O2 me-diated reaction of tertiary carbinols
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| Type |
Article
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