Access to di- and tri-Substituted Oxazoles via an NBS-Mediated Oxidative Cyclisation of N-acylaminoacid Derivatives†
IR@CDRI: CSIR-Central Drug Research Institute, Lucknow
View Archive Info| Field | Value | |
| Creator |
Bathula, S R
Reddy, M P Viswanadham, K K D R Sathyanarayana, Pochampalli Reddy, M S |
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| Date |
2013-10-04T09:35:46Z
2013-10-04T09:35:46Z 2013 |
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| Identifier |
European Journal of Organic Chemistry, 2013, 2013(21), 4552–4557
http://hdl.handle.net/123456789/1131 |
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| Description |
A remarkably simple method for the synthesis of various di- and tri-substituted functionalized oxazoles is described in metal or any catalyst free conditions. An iterative bromination and debromination of N-acylated aminoacid derivatives using NBS as the sole reagent cleanly led to various substituted oxazoles.
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| Format |
262983 bytes
application/pdf |
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| Language |
en
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| Relation |
CDRI Communication No. 8474
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| Subject |
Acyl amino acids
N-Bromosuccinamide Bromination Oxidative cyclisation Oxazoles |
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| Title |
Access to di- and tri-Substituted Oxazoles via an NBS-Mediated Oxidative Cyclisation of N-acylaminoacid Derivatives†
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| Type |
Article
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